BDBM19460 (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one::8-prenylnaringenin (8-PN)::AIDS095901::CHEMBL376915::YS04::cid_509245

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(-[#8])c2-[#6](=O)-[#6]-[#6@H](-[#8]-c12)-c1ccc(-[#8])cc1

InChI Key InChIKey=LPEPZZAVFJPLNZ-SFHVURJKSA-N

Data  10 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19460   

TargetEstrogen receptor(Homo sapiens (Human))
Ghent University

LigandPNGBDBM19460((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl...)
Affinity DataIC50:  57nMpH: 7.6 T: 2°CAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated polyvinyltoluene scintillation beads (Amersham) and biot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Ghent University

LigandPNGBDBM19460((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl...)
Affinity DataEC50:  7nMAssay Description:Estrogenic activity at estrogen receptor alpha in human Ishikawa cells assessed as induction of alkaline phosphatase activity using p-Nitrophenol pho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Ghent University

LigandPNGBDBM19460((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl...)
Affinity DataEC50:  5nMAssay Description:Estrogenic activity at ERalpha in human Ishikawa cells assessed as induction of alkaline phosphatase activity using p-nitrophenol as substrate treate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed